Depression

Depression is a common illness worldwide, with more than 264 million people affected.

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  • 271 trials currently open

Depression

Depression is a common illness worldwide, with more than 264 million people affected.

Depression is a serious mental health disorder affecting more than 300 million people worldwide. Symptoms may include feeling sad and hopeless for more than two weeks.

Depression (major depressive disorder or clinical depression) is a serious mental health mood disorder that affects more than 300 million people around the world.  Feelings of sadness and loss of interest in regular activities are some of the most recognizable symptoms, and how you think, feel, and behave can all be affected. Many find it difficult to do their normal, everyday activities including sleeping, eating, and working, and thus find their daily life significantly impaired.  In severe cases, thoughts of suicide may be present. Symptoms must be present for at least two weeks to be diagnosed with depression.  

TREATMENT

Treatment for depression usually consists of a combination of medication (antidepressants) and psychotherapy.  In severe cases, a period of hospitalization may be necessary if the patient is a threat to themselves or others.  According to the National Network of Depression Centers, over 80% of people who are treated for depression see an improvement in just four to six weeks after starting treatment.  Unfortunately, though, there is no one-size-fits-all solution, and only one-third of people suffering from depression actively seek treatment. With one in five Americans being impacted by depression at some point in their lifetimes (NNDC), research on effective treatments is becoming more and more critical.  Hundreds of clinical trials are being offered around the country and may be an effective way to discover new treatments.

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